Optical Spectroscopy Combined with HPLC-LIF to Differentiate Benign and Malignant Renal Tissues.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 105
- 试验地点
- 1
- 主要终点
- The fluorescence spectroscopy can be very useful to explore the mechanism involved during the progression of renal cancer. Along with multivariate data analysis the fluorescence spectra can give useful information for the objective diagnosis of tissue samples. The Raman spectrum and the HPLC-LIF protein profile can give complementary information of the tissue along with the LIF based diagnosis.
研究概览
简要总结
The spectroscopic techniques are emerging as an effective tool for detection of cancers in an effective way.This technique has a potential to be used as an alternative of biopsy which is called as optical biopsy.This single center observational study mainly aims the development of a compact device which is capable of acting like an optical biopsy device.Along with that the HPLC-LIF system will be giving the protein profiles of body fluids which in
turn gives the early signatures of renal cancer.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 95.00 Year(s)（—）
- 性别
- All
入选标准
- •All above 18 years of age and having malignant or benign type of kidney cancer (like clear cell renal cell carcinoma, urothelial carcinoma, chromophobe renal cell carcinoma, oncocytoma,angiomyolipoma and cystic renal cell carcinoma) are included.
排除标准
- •All male and female below age 18 are excluded.
结局指标
主要结局
The fluorescence spectroscopy can be very useful to explore the mechanism involved during the progression of renal cancer. Along with multivariate data analysis the fluorescence spectra can give useful information for the objective diagnosis of tissue samples. The Raman spectrum and the HPLC-LIF protein profile can give complementary information of the tissue along with the LIF based diagnosis.
时间窗: 3 years
次要结局
- It can be extended to different type of cancer such as breast cancer.(3 years)