Determining How Indoor Lighting Affects the Brain Health of Older Adults

Not Applicable

Recruiting

• Conditions: Social Isolation; Physical Activity; Cognitive Function; Sleep
• Interventions: Behavioral: Static Lighting Condition (L1); Behavioral: Dynamic Lighting Condition (L2); Behavioral: Dynamic Lighting Condition (L3)

• Registration Number: NCT05978934
• Lead Sponsor: Well Living Lab, Inc.

Brief Summary

The goal of this randomized, cross-over, single-site trial followed by an exploratory third intervention is to understand how indoor lighting affects different measures of brain health in older adults living in independent living residences. This is a community based study occurring in a local senior living facility. The main question this study aims to answer is:

- How does the quality of ambient indoor lighting an older adult is exposed to affect measures of brain health, such as sleep quality, physical activity, cognitive function, and social engagement?

Participants will be exposed to three different indoor lighting conditions for 4 weeks each while performing the following tasks:

* Wear a smartwatch throughout the study to measure sleep quality and physical activity

* Wear a small, wearable light sensor to measure light exposure during waking hours

* Perform cognitive assessments throughout the study to detect any changes between each of the lighting conditions

* Complete self-report of surveys to assess independence, social engagement, sleep quality, and mood

Results from these tasks will be compared within and between subjects to assess whether the different lighting conditions affect these different measures of brain health.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-04-27
• Study Start: 2023-05-15
• Status Verified: 2023-07
• Study First Submitted QC: 2023-07-28
• Last Update Submitted: 2023-07-28
• Study First Posted: 2023-08-07
• Last Update Posted: 2023-08-07
• Primary Completion: 2023-12
• Study Completion: 2023-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

1. At least age 60;
2. Able to wear wearable devices throughout the study;
3. Willing to have their lighting in their kitchen and dining areas changed and controlled for the study;
4. Willing to have environmental sensors placed in their residence;
5. Willing to provide contact information about their primary care provider (PCP); and
6. Able and has capacity to provide informed consent (score > 14.5 based on UBACC consent capacity form).

Exclusion Criteria

1. Is legally blind
2. Previously renovated their living units and no longer have the standard lighting installation offered by the Senior Living Facility;
3. Currently spend or plan to spend most of their day outside of their residence during the study (i.e., would not experience the indoor lighting intervention for the majority of the study);
4. Plan to travel to a different time zone during the study; or
5. Plan to be away from their residence for more than a week during the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
L2 then L1 followed by L3 lighting condition	Dynamic Lighting Condition (L2)	Participants will first experience a dynamic lighting condition (L2) then a static lighting condition (L1). After, participants will experience another dynamic lighting condition (L3) with increased morning brightness compared to L2.
L1 then L2 followed by L3 lighting condition	Static Lighting Condition (L1)	Participants will first experience a static lighting condition (L1) then a dynamic lighting condition (L2). After, participants will experience another dynamic lighting condition (L3) with increased morning brightness compared to L2.
L1 then L2 followed by L3 lighting condition	Dynamic Lighting Condition (L2)	Participants will first experience a static lighting condition (L1) then a dynamic lighting condition (L2). After, participants will experience another dynamic lighting condition (L3) with increased morning brightness compared to L2.
L2 then L1 followed by L3 lighting condition	Static Lighting Condition (L1)	Participants will first experience a dynamic lighting condition (L2) then a static lighting condition (L1). After, participants will experience another dynamic lighting condition (L3) with increased morning brightness compared to L2.
L1 then L2 followed by L3 lighting condition	Dynamic Lighting Condition (L3)	Participants will first experience a static lighting condition (L1) then a dynamic lighting condition (L2). After, participants will experience another dynamic lighting condition (L3) with increased morning brightness compared to L2.
L2 then L1 followed by L3 lighting condition	Dynamic Lighting Condition (L3)	Participants will first experience a dynamic lighting condition (L2) then a static lighting condition (L1). After, participants will experience another dynamic lighting condition (L3) with increased morning brightness compared to L2.

Primary Outcome Measures

Name	Time	Method
Wake After Sleep Onset	Change in wake after sleep onset per night over the course of each condition of the 16-week study.	Wake after sleep onset per night in minutes as measured daily by a wearable device.
Total Sleep Time	Change in total sleep time per night over the course of each condition of the 16-week study.	Total sleep time per night in minutes as measured daily by a wearable device.
Sleep State Duration	Change in sleep state duration per night over the course of each condition of the 16-week study.	Sleep state duration per night in minutes as measured daily by a wearable device.

Secondary Outcome Measures

Name	Time	Method
Sleep Quality	Change in self-reported sleep quality over the course of each condition of the 16-week study.	Self-report measurement of perceived sleep quality made daily via the Groningen Sleep Quality Survey.
Steps Taken	Change in physical activity in steps per day over the course of each condition of the 16-week study.	Physical activity in steps per day as measured daily by a wearable device.
Self-Reported Loneliness	Change in self-reported loneliness over the course of each condition of the 16-week study.	Self-report measurement of loneliness assessed weekly via the UCLA Loneliness Scale.
Self-Reported Depression	Change in self-reported depression over the course of each condition of the 16-week study.	Self-report measurement of depression assessed weekly via the Positive and Negative Affect Scale.
Physical Activity	Change in physical activity in minutes per day over the course of each condition of the 16-week study.	Physical activity in minutes per day as measured daily by a wearable device.
Sustained-Attention Reaction Time	Change in sustain-attention reaction time performance over the course of each condition of the 16-week study.	Task performance on a sustained-attention reaction time assessment taken twice weekly.
Self-Reported Mood	Change in self-reported mood over the course of each condition of the 16-week study.	Self-report measurement of mood assessed weekly via the Depression, Anxiety, and Stress Scale.
Working Memory	Change in working memory performance over the course of each condition of the 16-week study.	Task performance on a working memory assessment taken twice weekly.
Task Switching	Change in task switching performance over the course of each condition of the 16-week study.	Task performance on a task switching assessment taken twice weekly.
Response Inhibition	Change in response inhibition performance over the course of each condition of the 16-week study.	Task performance on a response inhibition assessment taken twice weekly.

Trial Locations

Locations (1)

The Waters on Mayowood; 🇺🇸 Rochester, Minnesota, United States