Detection of Right Ventricular Dysfunction by Portal Vein Doppler After Cardiac Surgery
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Postoperative Complications
- Sponsor
- CMC Ambroise Paré
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Right ventricular failure
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Right ventricular (RV) failure after cardiac surgery is associated with morbidity and mortality, but is hard to diagnose with conventional echocardiographic means. RV dysfunction may be associated with hepatic congestion, which may have an effect on portal veinous flow, but this has not been extensively. The investigators aimed determine whether an increased pulsatility in the portal venous flow was associated with RV dysfunction, after cardiac surgery at risk of RV dysfunction: mitral and tricuspid valve procedures.
Detailed Description
In cardiac surgical patients, RV dysfunction is associated with organ hypoperfusion and venous congestion leading to increased morbidity and mortality. Non-invasive methods used to assess RV function are 2D-echocardiographic measurement of tricuspid annular plane systolic excursion (TAPSE), RV ejection fraction (EF), RV fractional area change (FAC), 3D assessment of RV function, tissue Doppler assessment of velocities, and magnetic resonance imaging (MRI). Though MRI is the gold standard method to assess RV function, it cannot be used in the perioperative period. In the present prospective observational study, The investigators investigated the association between the pattern of portal venous flow and RV function as assessed by echocardiography in the postoperative period.
Investigators
Eligibility Criteria
Inclusion Criteria
- •More than 18 years old
- •Ability to provide an informed consent
- •Planned mitral and / or tricuspid valve surgery under cardiopulmonary bypass.
Exclusion Criteria
- •Insufficient echogenicity
Outcomes
Primary Outcomes
Right ventricular failure
Time Frame: First 24 hours post cardiac surgery
1. systolic dysfunction (TAPSE below 16 mm or S wave below 9.5 cm/s) 2. RV fractional area change below 35% 3. End-diastole diameter ratio between RV and left ventricle \> 0.6 4. Ratio between S and D wave or inverse D wave in supra-hepatic veins
Portal flow measured by Doppler
Time Frame: First 24 hours post cardiac surgery
flow pulsatility is assessed with the formula = 100 x (Vmax-Vmin)/Vmax. Time frame: First 24 hours post cardiac surgery
Secondary Outcomes
- Echocardiographic acquisition(First 24 hours post cardiac surgery)
- Concordance of pulsatile flow assessment(First 24 hours post cardiac surgery)
- Concordance of RV dysfunction measurements(First 24 hours post cardiac surgery)
- Preoperative RV dysfunction(30 days before cardiac surgery)
- Acute kidney injury(one week after surgery)
- Cholestasis(one week after surgery)