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The phaseI,II study of neoadjuvant chemotherapy of gemcitabine+nab-paclitaxel+S-1 for patients with locally-advanced pancreatic cancer

Phase 1
Conditions
locally-advanced pancreatic cancer
Registration Number
JPRN-UMIN000016630
Lead Sponsor
Hiroshima University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

(1)severe allegy for medicine (2)Patients with other malignant disease within 5 years (3)Patients with active infection (4)Patients with severe neuropathy(>Grade2) (5)Patients with ileus (6)Patients with interstitial pneumonia (7)Patients with uncontrallable ascites or pleural fluid (8)Patients with uncontrallable diabetes (9)Patients with uncontrallable heart disease (10)Patients with pregnant or possibly pregnant (14)Patients who have judged not suitable for this study by doctor.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Phase I: incidence of adverse enent which apply for discontinuance criteria Phase II: 2 year survival rate, median survival time
Secondary Outcome Measures
NameTimeMethod
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