MedPath

Assessment of Palm date (Phoenix dactylifera L.) on clinical manifestation of knee Osteoarthritis

Phase 3
Conditions
Osteoarthritis of Knee.
Osteoarthritis of knee
Registration Number
IRCT20180126038510N1
Lead Sponsor
Tabriz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
94
Inclusion Criteria

Mild to moderate knee Ostoarthritis patients according to Kellegren-Lawrence (K-L) grading scale
Pain at least in one knee in last 3 month ago
Minimum annoying pain in last (at least ) 4 week before randomized selection according to VAS scale

Exclusion Criteria

Allergy to topical preparation of Date palm and Diclofenac gel
Skin lesion on the knee
Secondary Osteoarthritis as Rhuomatoid arthritis,Gout,Infectious arthritis,Metabolic arthritis,Traumatic arthritis
Operative knee joint replacement
Topical or systemic steroid use since 14 day before study
Intraarticular steroid injection since 90 day before study
Pregnancy and lactation period
Alcohol and opioid addiction
Radiculopathy and Neuropathy
History of any kind of knee operation and trauma
Utilization of other analgesic drugs since study period
Nonconformity of life style according to knee health

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Score of knee pain intensity. Timepoint: Measuring the Score of knee pain intensity at the beginning of the study and 14 and 28 days after starting use of Palm date ointment. Method of measurement: Visual Analogue Scale And Western Ontario and McMaster Universities Osteoarthritis questionnaire.;Score of knee stiffness intensity. Timepoint: Measuring Score of knee stiffness intensity at the beginning of the study and 14 and 28 days after starting use of Palm date ointment. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis questionnaire.
Secondary Outcome Measures
NameTimeMethod
Daily activity Score. Timepoint: Measuring of Daily activity Score at the beginning of the study and 14 and 28 days after starting use of Palm date ointment. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis questionnaire.
© Copyright 2025. All Rights Reserved by MedPath