Chocolate's Effect on the Cerebral Vasculature

Completed

• Conditions: Cerebral Vasculature
• Interventions: Other: cocoa

• Registration Number: NCT01507259
• Lead Sponsor: NHS Greater Glasgow and Clyde

Brief Summary

The popularity of chocolate can largely be attributed to its mood elevating properties, research shows that it contains antioxidants that also provide physical health benefits. Dark chocolate, in particular, contains high levels of an antioxidant called epicatechin, which is known to cause changes in blood vessels by relaxing them and increasing blood flow.

Little is know about the immediate effects of chocolate consumption, or the differences between milk and dark chocolate with regards to these effects. The project will investigate the effect of a single bar of dark or milk chocolate upon blood flow to the brain, using simple ultrasound tests.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-01-06
• Study First Submitted QC: 2012-01-09
• Study First Posted: 2012-01-10
• Study Start: 2012-02
• Study Completion: 2012-02
• Status Verified: 2012-07
• Last Update Submitted: 2012-07-26
• Last Update Posted: 2012-07-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• No regular medication including vitamins/antioxidants
• Able to provide informed consent

Exclusion Criteria

• Inability to perform breath-hold test
• Any known cardiovascular disease, diabetes, throid disease, high blood pressure, hyperlipidaemia or pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
100 g containing 70% or 34% cocoa	cocoa	Healthy controls

Trial Locations

Locations (1)

Western Infirmary; 🇬🇧 Glasgow, United Kingdom