Changes of Higher-Order Aberrations After Different Types of LASIK in Myopia

Not Applicable

Not yet recruiting

• Conditions: Conventional LASIK, Femto-LASIK and PRK in Low and Moderate Myopia

• Registration Number: NCT06860061
• Lead Sponsor: Sohag University

Brief Summary

This prospective comparative interventional study will enroll patients with low and moderate myopia who seek laser vision correction at Sohag Center for LASIK and Corneal Surgeries, Sohag, Egypt. Eyes included will be divided into 3 groups according to the type of refractive surgery used (conventional LASIK, Femto-LASIK and PRK) and each group will be subdivided into 2 groups according to the degree of myopia (low and moderate).

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-02
• Study First Submitted: 2025-02-19
• Study Start: 2025-03
• Study First Submitted QC: 2025-03-01
• Last Update Submitted: 2025-03-01
• Study First Posted: 2025-03-05
• Last Update Posted: 2025-03-05
• Primary Completion: 2026-02
• Study Completion: 2026-02

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Age: 18 - 45 years old.

Refraction:

Low and moderate grades of myopia will be included:

(According to manifest refraction) low ([0] - ≤ [-3] diopters) Moderate ([-3] - ≤ [-6] diopters) With cylinder ≤ [-1.5] diopters.

Exclusion Criteria

Any ocular surgery or medication, corneal opacities, pregnancy, lactation and keratoconus.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Changes of corneal higher-order aberrations	1 year	Corneal aberrometry will be performed using Sirius's Scheimpflug-Placido topography (CSO, Florence, Italy).
Changes of total ocular higher-order aberrations	1 year	Wavefront refraction will be acquired by the iDesign aberrometer (Hartmann-Shack Aberrometer)