Blood Pressure Lowering and Platelet Inhibitory Effects of Juices from Pachyrhizus erosus L. root and Psidium guajava L. fruit: a Control Study in Healthy Volunteers.

Phase 1

Completed

• Conditions: Cardiovascular problems including hypertension and platelet hyperactivity.; Yam been root juice; Guava fruit juice; Circulating nitrate; Circulating nitrite; Blood pressure lowering effect; Platelet inhibitory effect; Plasma cGMP

• Registration Number: TCTR20150228001
• Lead Sponsor: The Thailand Research Fund (TRF)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2013-12-17
• Study Start: 2015-02-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Age between 20 to 45 years.
2. Body mass index (BMI) of 18-27 kg per square meter.

Exclusion Criteria

1. History of any serious illnesses, including infectious diseases, cardiovascular and pulmonary diseases.
2. Smoking and/or alcoholic drinking.
3. Systemic medication (other than the oral contraceptive pill).
4. Pregnancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood pressure and heart rate 0, 0.5, 1, 1.5, 2, 2.5, 3, 5 hours Blood pressure and heart rate monitoring

Secondary Outcome Measures

Name	Time	Method
Platelet function 0, 2.5, 5 ours Platelet aggregation assessment