Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: a Relation to Periodontal Inflammaging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Clinical attachment loss
研究概览
简要总结
Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: A Relation to Periodontal Inflammaging
详细描述
Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: A Relation to Periodontal Inflammaging
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or Female
- •Aged below 40 or above
- •Have at least 16 natural teeth excluding wisdom.
- •Provide informed consent and willingness to cooperate with study protocol.
- •Periodontitis stage II patients (23):
- •CAL from 3-4 mm.
- •Radiographic bone loss (15% to 33%).
- •No tooth loss due to periodontitis.
- •Maximum probing depth ≤ 5 mm, mostly horizontal bone loss
排除标准
- •1- Patients with any smoking habits 2- History of antibiotics in the previous three months. 3- Pregnant or lactating female. 4- Treatment with any systemic drug. 5- History of systemic disease. 6- Patients who received periodontal treatment in the last 6 months
研究组 & 干预措施
conventional scaling and debridement young age patient
conventional scaling and debridement young age patient
干预措施: conventional scaling and debridement (Procedure)
conventional scaling and debridement old age patient
conventional scaling and debridement old age patient
干预措施: conventional scaling and debridement (Procedure)
diode laser as adjunctive to scaling and debridement young age patient
diode laser as adjunctive to scaling and debridement young age patient
干预措施: Diode laser as adjunctive to conventional scaling and debridement (Radiation)
diode laser as adjunctive to scaling and debridement old age patient
diode laser as adjunctive to scaling and debridement old age patient
干预措施: Diode laser as adjunctive to conventional scaling and debridement (Radiation)
结局指标
主要结局
Clinical attachment loss
时间窗: Base line , follow up after 1 month , second follow up after 6 months
Gingival index
时间窗: base line, follow up after 1 month, second follow up after 6 months
Toll like receptor - 4
时间窗: base line, follow up after 1 month, second follow up after 6 months
次要结局
未报告次要终点
研究者
Rawda Saleh Saad Alashmawy
dentist
Misr University for Science and Technology