Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 3
- 主要终点
- stoke volume index
研究概览
简要总结
The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children. Children who need volume expansion will receive colloid 10 mL/kg. Blood pressure, heart rate, central venous pressure, systolic pressure variation, pulse pressure variation, delta down, aortic blood flow velocity variation, inferior vena cava diameter variation, and pleth variability index will be measure before and after volume expansion. Patients will be classified as responders to volume loading if stoke volume index increase by at least 15%.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- — 至 8 Years(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •neurosurgery under general anesthesia
- •< 8 years old
排除标准
- •cardiac disease
- •pulmonary, renal and hepatic disease
- •infectious disease
- •hematologic and muscular disease
结局指标
主要结局
stoke volume index
时间窗: before and after volume loading (20 minutes)
Volume loading will be performed for 20 minutes. Stroke volume will be meausred before and after volume expansion
次要结局
未报告次要终点
研究者
Jin-Tae Kim
assistant professor
Seoul National University Hospital
