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临床试验/NCT01364103
NCT01364103已完成不适用

Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery

Seoul National University Hospital3 个研究点 分布在 2 个国家目标入组 33 人开始时间: 2011年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
33
试验地点
3
主要终点
stoke volume index

研究概览

简要总结

The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children. Children who need volume expansion will receive colloid 10 mL/kg. Blood pressure, heart rate, central venous pressure, systolic pressure variation, pulse pressure variation, delta down, aortic blood flow velocity variation, inferior vena cava diameter variation, and pleth variability index will be measure before and after volume expansion. Patients will be classified as responders to volume loading if stoke volume index increase by at least 15%.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
— 至 8 Years(Child)
性别
All
接受健康志愿者

入选标准

  • neurosurgery under general anesthesia
  • < 8 years old

排除标准

  • cardiac disease
  • pulmonary, renal and hepatic disease
  • infectious disease
  • hematologic and muscular disease

结局指标

主要结局

stoke volume index

时间窗: before and after volume loading (20 minutes)

Volume loading will be performed for 20 minutes. Stroke volume will be meausred before and after volume expansion

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jin-Tae Kim

assistant professor

Seoul National University Hospital

研究点 (3)

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