CTRI/2012/07/002761
Recruiting
未知
Effect of atorvastatin on hyperlipidemia and progression of carotid intima media thickness in steroid resistance nephrotic syndrome: A randomized controlled trial
ICMR0 sites50 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: null- Steroid Resistant Nephrotic Syndrome with hyperlipidemia
- Sponsor
- ICMR
- Enrollment
- 50
- Status
- Recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\)Patient with LDL Cholesterol Between 130\-300mg/dl on 2 occassions at least one week apart.
- •2\)Patient with stable dose of immunosuppressive medication (Prednisolone and Calcineurin inhibitors)for aperiod of 3 months.
Exclusion Criteria
- •1\) History of jaundice in last 6 months: AST/ALT levels more than twice normal of upper limit of the laboratory reference value.
- •2\) CPK levels more than 3 times normal.
- •3\) Children on lipid lowering agents such asHMG CoA reductase inhibitors in the past 3 months.
- •4\)Family History of premature CVD
- •5\)Patients with secondary nephrotic syndrome(SLE,IgAN,MPGN,MGN Alports disease)
- •6\)Patients on pulse corticosteroids or cyclophosphamide in last 6 months.
- •7\)Patients with stage 2 hypertension.
- •8\)GFR30ml/min/m2 or below
- •9\)Children residing beyond 200km from delhi.
Outcomes
Primary Outcomes
Not specified
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