PET-AML - Value of 18FDG-PET-CT in Patients With AML for Detection of Extramedullary AML Manifestations
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 93
- 试验地点
- 1
研究概览
简要总结
Myeloid Sarcoma (or granulocytic Sarcoma or Chloroma) is well defined by the WHO. However, there are currently no data about the prevalence, sites of occurence and thr prognostic value for patients with AML with this finding. Information about this condition is based on retrospective analyses since there have been no studies trying to define the role of myeloid sarcoma in AML so far. This observational trial will include adult patients with newly diagnosed and relapsed AML in order to perform 18FDG-PET-CT imaging prior to induction chemotherapy. Furthermore, a second 18FDG-PET-CT will be performed after induction chemotherapy to define the responsiveness of these tumors to chemotherapy. The primary endpoint of this study is the prevalence of 18FDG-PET-CT positive extramedullary AML manifestations (myeloid sarcoma) in patients with newly diagnosed or relapsed AML.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with newly diagnosed or relapsed AML
- •AML FAB M0-2, M4-7
- •Signed informed consent after patient information
- •Male and female patients with AML age 18-80
- •18FDG-PET-CT is available within a period of 5 days after diagnosis of AML
排除标准
- •AML FAB M3 (Promyelocytic Leukemia)
- •lacking willingness to cooperate
- •pregnancy or insufficient contraception
- •18FDG-PET-CT is not available within a period of 5 days after diagnosis of AML
- •Medical condition of the patients requires an immediated start of chemotherapy
研究者
Friedrich Stölzel, M.D.
PET-AML - Value of 18FDG-PET-CT in Patients With AML for Detection of Extramedullary AML Manifestations
Technische Universität Dresden