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Clinical Trials/NCT05881629
NCT05881629
Recruiting
Not Applicable

Early Diagnosis and Intervention for Fetal Malposition in Active Labor and Its Impact on Mode of Delivery: A Randomized Controlled Trial

Women and Infants Hospital of Rhode Island1 site in 1 country200 target enrollmentMay 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cesarean Delivery Affecting Fetus
Sponsor
Women and Infants Hospital of Rhode Island
Enrollment
200
Locations
1
Primary Endpoint
Operative Delivery Rate
Status
Recruiting
Last Updated
7 months ago

Overview

Brief Summary

The goal of this randomized trial is to test if changing a person's position in labor can increase the chances of delivering their baby vaginally.

Specifically, it aims to answer the questions:

  • In fetuses who are facing upwards (occiput posterior, OP) or sideways (occiput transverse, OT) during labor, does changing the patient's position during active labor to a side-lying posture with a peanut ball increase the chances of them having a successful, spontaneous vaginal delivery?
  • Does changing the patient's position in active labor affect the position of the baby at the time of delivery?
  • Do intentional position changes in labor impact patient-perceived autonomy during their labor and delivery experience?

Participants will:

  • Receive an ultrasound during labor to determine the position of their baby
  • Be asked to adopt a specific position in labor (side-lying with peanut ball) if they are randomized to the study group
  • Receive additional ultrasounds during labor to assess their baby's position
  • Fill out a questionnaire about their labor experience following the delivery of their baby

Detailed Description

In this randomized trial, the investigators aim to evaluate the effects of early ultrasound diagnosis and active management of fetal malposition during the first stage of labor. Specifically, the investigators will compare the modified Sims (side-lying) position ipsilateral to fetal spine with the addition of a peanut ball versus free maternal position choice in occiput posterior (OP) or occiput transverse (OT) fetuses diagnosed by ultrasound during active labor, defined as greater than 6cm cervical dilation. The primary outcome will be operative delivery rates, defined as either cesarean delivery or instrumental vaginal delivery with vacuum or forceps. The investigators will also assess rates of spontaneous rotation to occiput anterior (OA) position at complete dilation and at delivery, as well as the impact of the position changes on the patient's labor experience and their perceived autonomy.

Registry
clinicaltrials.gov
Start Date
May 1, 2024
End Date
September 1, 2026
Last Updated
7 months ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Women and Infants Hospital of Rhode Island
Responsible Party
Principal Investigator
Principal Investigator

Kathryn Anderson

Resident physician

Women and Infants Hospital of Rhode Island

Eligibility Criteria

Inclusion Criteria

  • Maternal age \>18
  • Term gestation (\>37 weeks)
  • Singleton pregnancy
  • Spontaneous or induced active labor (cervical dilation 6-9cm)
  • Epidural anesthesia
  • Cephalic fetal presentation, OP/OT position diagnosed by bedside ultrasound
  • Continuous external fetal monitoring
  • Ability to consent

Exclusion Criteria

  • Multiple gestations
  • Unanesthetized labor
  • Known fetal anomalies
  • Known intrauterine fetal demise
  • Inability to consent

Outcomes

Primary Outcomes

Operative Delivery Rate

Time Frame: Enrollment in active labor through delivery, on average 12 hours

The combined rate of cesarean and instrumental vaginal deliveries in each study group

Secondary Outcomes

  • Estimated Blood Loss(Time of delivery to 24 hours postpartum)
  • Duration of Active Second Stage(Onset of second stage of labor to delivery, up to 4 hours)
  • Score on Labor Agentry Scale(Time of delivery to discharge from hospital, on average 2 days)
  • Rotation at Complete Dilation(Enrollment in active labor through delivery, on average 12 hours)
  • Rotation at Delivery(Enrollment in active labor through delivery, on average 12 hours)
  • Apgar Scores(Time of delivery to 5 minutes postpartum)
  • Degree of Laceration following Delivery(Time of delivery to admission to postpartum unit, on average 2 hours)
  • Neonatal Intensive Care Unit (NICU) Admission(Time of delivery to up to 6 weeks postpartum)

Study Sites (1)

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