Assessment of efficacy of antenatal betamethasone on neonatal respiratory outcome of late preterm delivery (34-37 weeks)

Phase 2

• Conditions: Respiratory distress syndrome of newborn.; Respiratory distress syndrome of newborn

• Registration Number: IRCT20120918010876N3
• Lead Sponsor: Shahid Beheshti University of Medical Sciences- Mahdieh Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

Singleton pregnancy
Gestational age from 34 weeks and 0 days to 36 weeks and 6 days
High probability of preterm labor (in weeks 37-34) due to premature rupture of membranes
Preterm labor with intact membranes
preterm labor with any indication (including previous cesarean section, intrauterine growth retardation (IUGR), Oligohydramnios, pre-eclampsia, etc.)

Exclusion Criteria

No exact gestational age (unknown firt day of last menstrual period (LMP) or no ultrasound dating)
Cervix dilatation of 4 cm or more
Planned delivery after 36 weeks and 6 days
Known congenital malformations
Received corticosteroids before week 34 or for other indications
Fetal death
Major fetal anomaly
Non-viable fetus
Gestational diabetes
Diabetes before pregnancy
Maternal contraindications for betamethasone
Chorioamnionitis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
eonatal respiratory outcomes. Timepoint: After delivery until patient discharge. Method of measurement: Clinical symptoms & signs.;NICU admission. Timepoint: After delivery until patient discharge. Method of measurement: Clinical symptoms & signs.;Hospitalization duration. Timepoint: Patient discharge time. Method of measurement: Hospitalization duration in day and hour.