Interventions for Depressed Low Income Mothers and Their Infants

Not Applicable

Completed

• Conditions: Depression
• Interventions: Behavioral: Maternal interpersonal psychotherapy (IP); Behavioral: Informational meetings plus treatment as usual; Behavioral: Infant-parent psychotherapy

• Registration Number: NCT00105573
• Lead Sponsor: University of Rochester

Brief Summary

This study will compare three interventions for depressed, low income mothers and determine which is most effective in treating maternal depression and in fostering development in infants.

Detailed Description

Poorly educated, low income mothers are at high risk for becoming depressed. The effects of living in poverty and being reared by a depressed parent can be detrimental to an infant's development. Effective interventions to reduce maternal depression and strengthen the mother-infant relationships are needed.

Participants will be randomly assigned to one of three groups. Group 1 mothers will receive 16 weekly sessions of interpersonal psychotherapy (IP) designed to directly treat maternal depression. Group 1 participants will have monthly follow-up visits for 1 year. Participants in Group 2 will receive 16 weekly sessions of IP followed by 1 year of in-home, infant-parent psychotherapy, an intervention addressing relationship difficulties between depressed mothers and their infants. Group 3 mothers will be invited to attend informational meetings as well as be referred to local services available to people with depression.

All mother-child pairs will be evaluated when the child is 12, 16, 24, and 36 months of age. Evaluations will involve questionnaires, diagnostic interviews, developmental assessments, and video- and audio-taped measures.

Study Timeline

• Study Start: 2004-01
• Study First Submitted: 2005-03-15
• Study First Submitted QC: 2005-03-15
• Study First Posted: 2005-03-16
• Primary Completion: 2010-04
• Study Completion: 2010-04
• Status Verified: 2013-04
• Last Update Submitted: 2013-04-29
• Last Update Posted: 2013-04-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 218

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Interpersonal psychotherapy/child-parent psychotherapy	Infant-parent psychotherapy	Participants will receive interpersonal psychotherapy for depression plus 1 year of in-home, child-parent psychotherapy.
Interpersonal Psychotherapy	Maternal interpersonal psychotherapy (IP)	Participants will receive interpersonal psychotherapy for depression.
Interpersonal psychotherapy/child-parent psychotherapy	Maternal interpersonal psychotherapy (IP)	Participants will receive interpersonal psychotherapy for depression plus 1 year of in-home, child-parent psychotherapy.
Enhanced community standard	Informational meetings plus treatment as usual	Participants will be invited to attend informational meetings as well as be referred to local services available to people with depression.

Primary Outcome Measures

Name	Time	Method
Maternal depression	Measured when the child is 12, 16, 24, 36, and 48 months of age
Child development	Measured when the child is 12, 16, 24, 36, and 48 months of age
Infant-parent attachment	Measured when the child is 12, 16, 24, 36, and 48 months of age

Trial Locations

Locations (1)

Mount Hope Family Center; 🇺🇸 Rochester, New York, United States