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临床试验/CTRI/2023/02/049519
CTRI/2023/02/049519尚未招募2 期

Prospective Evaluation of Acute Toxicity and Loco Regional Control in Post-Operative Oral Cavity Squamous Cell Carcinoma Treated with Moderately Hypofractionated Intensity Modulated Radiation Therapy - AVIATOR

Dr RMLIMS Lucknow0 个研究点目标入组 0 人开始时间: 待定最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

入选标准

  • 1. Post-operative patients (age 18-80 years) of oral cavity squamous cell carcinoma (excluding lip).
  • 2. Karnofsky performance status 70 or above
  • 3. One or more of the following risk factors: pT3/pT4, Node positive, Close margin (1-5mm), Perineural invasion present, Lympho-vascular invasion present, depth of invasion >= 4mm for tongue and >=7 mm for buccal mucosa
  • 4. Patients with indications for chemo-radiation but who are
  • 5. unfit for chemotherapy due to associated comorbid conditions or poor GC
  • 6. unwilling to undergo chemotherapy

排除标准

  • 1. Patients with absolute indications for concurrent chemo-radiotherapy (margin positive disease, extra-capsular extension)
  • 2. Patients who have received neoadjuvant chemotherapy.
  • 3. Any histopathology other than SCC
  • 4. Previous radiotherapy to the head and neck region
  • 5. Patients with absolute indications for concurrent chemoradiotherapy.
  • 6. Synchronous or metachronous malignancy
  • 7. Pregnant or lactating women
  • 8. Uncontrolled concurrent illness like DM, HTN

研究者

发起方
Dr RMLIMS Lucknow

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