NL-OMON44326
Completed
Not Applicable
Genes involved in the induction and resolution of eczema using the Atopy Patch Test as an in vivo model for atopic dermatitis - APT and markers for eczema
niversitair Medisch Centrum Utrecht0 sites10 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- atopic dermatitis (AD)
- Sponsor
- niversitair Medisch Centrum Utrecht
- Enrollment
- 10
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •age 18\-70 years
- •positive APT
Exclusion Criteria
- •Active AE on the patients back
- •\- Not sensitized to aeroallergens, such as house dust mite (demonstrated by a positive immuno CAP test for these allergens)
- •\- Treatment with systemic immunosuppressive medication (including corticosteroids and cyclosporin) within the 4 weeks prior to having the biopsies performed. In addition, weekly use of equal or more than 50 grams of topical corticosteroids class IV or weekly use of equal or more than 100 grams of topical corticosteroids class III.
- •\- Exposure of biopsy location to high levels of UV radiation (e.g. UV\-therapy, use of tanning booths, sunbathing) in the 2 weeks prior to taking biopsies
- •\- Use of antihistamines in the week or days before and during the APT ( see patientinformation 'Bijlage 4: medicatielijst')
Outcomes
Primary Outcomes
Not specified
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