Prediction Model for Inadequate Weight Loss After Sleeve Gastrectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Area under receiver operating characteristic curve (AUC) of the prediction model
研究概览
简要总结
This study aims to develop and validate a prediction model for estimating the probability of inadequate weight loss one year after sleeve gastrectomy.
详细描述
Inadequate weight loss (IWL) is a major problem after sleeve gastrectomy, leading to the recurrence of obesity-related comorbidities and increased risk of revision surgery. It is important to identify the high-risk individuals for IWL before surgery so that clinicians can initiate more rigorous weight monitoring and management strategies. Therefore, this study aims to develop a prediction model using preoperative clinical and laboratory data to estimate the risk of IWL one year after sleeve gastrectomy, and then validate it using two separate datasets.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 16 Years 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI ≥ 27.5 kg/m2;
- •16 years ≤ age ≤ 70 years;
- •Complete preoperative data and one-year follow-up information
排除标准
- •Patients who did not undergo SG;
- •Incomplete follow-up information;
- •Patients with a history of pituitary or thyroid disease;
- •Female patients who conceived within one year after surgery
结局指标
主要结局
Area under receiver operating characteristic curve (AUC) of the prediction model
时间窗: 1 year
AUC reflects the discriminatory ability of the model, which was measured in this study.
次要结局
- Brier score of the prediction model(1 year)
研究者
Yuntao Nie
Medical doctor
China-Japan Friendship Hospital