Improving Adherence to Pharmacological Treatment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 689
- 试验地点
- 2
- 主要终点
- The primary outcome evaluated is the percentage of patients with a serum low-density lipoprotein cholesterol (LDL-C) level <70 mg/dl.
研究概览
简要总结
The overall goal of this study was to implement and evaluate the effects of a systems-based and pharmacist-mediated program designed to improve adherence for patients with known coronary heart disease (CHD) to lipid-lowering pharmacologic therapy and of their physicians/nurse practitioners to the National Cholesterol Education Program Guidelines.
详细描述
Patients were randomly assigned to a usual care condition which consisted of patients provided with usual care only, or to the Special Intervention (SI) condition. The intervention was implemented and coordinated by pharmacists, who utilized for tracking and communication the Lotus Notes®-based system that was developed for the project.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •was between 30 and 85 years of age;
- •had known CHD, defined as the presence of at least one coronary lesion at coronary angiography of >50%.
排除标准
- •was unable or unwilling to give informed consent;
- •had a history of intolerance to two or more statin drugs;
- •planned to move out of the area within one year of recruitment;
- •had a poor prognosis such that life expectancy was thought to be <5 years;
- •had a psychiatric illness which limited ability to participate; or
- •had no telephone.
结局指标
主要结局
The primary outcome evaluated is the percentage of patients with a serum low-density lipoprotein cholesterol (LDL-C) level <70 mg/dl.
时间窗: One year
次要结局
- Proportion of prescribed lipid-lowering medication taken by patients as measured by a continuous multiple-interval (CMA) measure of medication availability based on pharmacy records.(One year)