Impact Of Posture and Prolonged Pneumoperitoneum on Intra-Operative and Postoperative Outcomes During Gynecological Laparoscopic Surgery: An Observational Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- mean arterial blood pressure
研究概览
简要总结
Laparoscopic surgery is now widely established.Laparoscopic surgery involves insufflation of a gas (usually carbon dioxide) into the peritoneal cavity producing a pneumoperitoneum. The raised intra-abdominal pressure of the pneumoperitoneum, alteration in the patient's position and effects of carbon dioxide absorption cause changes in physiology, especially within the cardiovascular and respiratory systems.
详细描述
The study will be carried out after approval of the ethical committee of Faculty of Medicine, Assiut University. A full preoperative anesthetic assessment will be carried out. Particular attention to the cardiovascular and respiratory systems is essential because of potential effects of the pneumoperitoneum and patient position.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age range 18-50
- •Elective gynecological laparoscopic surgery
排除标准
- •Severe ischemic or valvular heart disease
- •Increased intracranial pressure (e.g. Hydrocephalus, Cerebral tumor, Head injury)
- •Hepatic or renal impairment
- •Emergency surgery
- •Open surgery
- •Previous abdominal surgery
结局指标
主要结局
mean arterial blood pressure
时间窗: within the duration of the operation
mean arterial blood pressure will be monitored at different times
Pulmonary function tests
时间窗: within the first 24 hours
forced expiratory volume at one second
次要结局
- PaO2(within the first 24 hours)
- Arterial to end-tidal PaCO2- difference(within the first 24 hours)
- Analgesic requirement(within the first 24 hours)
- Postoperative nausea and vomiting(within the first 24 hours)
- Intra-abdominal pressure(within the first 24 hours)
研究者
Sayed Kaoud Abd-Elshafy
Associate Profossor
Assiut University