Impact Of Posture and Prolonged Pneumoperitoneum on Intra-Operative and Postoperative Outcomes During Gynecological Laparoscopic Surgery: An Observational Clinical Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Laparoscopy
- Sponsor
- Assiut University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- mean arterial blood pressure
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Laparoscopic surgery is now widely established.Laparoscopic surgery involves insufflation of a gas (usually carbon dioxide) into the peritoneal cavity producing a pneumoperitoneum. The raised intra-abdominal pressure of the pneumoperitoneum, alteration in the patient's position and effects of carbon dioxide absorption cause changes in physiology, especially within the cardiovascular and respiratory systems.
Detailed Description
The study will be carried out after approval of the ethical committee of Faculty of Medicine, Assiut University. A full preoperative anesthetic assessment will be carried out. Particular attention to the cardiovascular and respiratory systems is essential because of potential effects of the pneumoperitoneum and patient position.
Investigators
Sayed Kaoud Abd-Elshafy
Associate Profossor
Assiut University
Eligibility Criteria
Inclusion Criteria
- •Age range 18-50
- •Elective gynecological laparoscopic surgery
Exclusion Criteria
- •Severe ischemic or valvular heart disease
- •Increased intracranial pressure (e.g. Hydrocephalus, Cerebral tumor, Head injury)
- •Hepatic or renal impairment
- •Emergency surgery
- •Open surgery
- •Previous abdominal surgery
Outcomes
Primary Outcomes
mean arterial blood pressure
Time Frame: within the duration of the operation
mean arterial blood pressure will be monitored at different times
Pulmonary function tests
Time Frame: within the first 24 hours
forced expiratory volume at one second
Secondary Outcomes
- PaO2(within the first 24 hours)
- Arterial to end-tidal PaCO2- difference(within the first 24 hours)
- Analgesic requirement(within the first 24 hours)
- Postoperative nausea and vomiting(within the first 24 hours)
- Intra-abdominal pressure(within the first 24 hours)