Metabolic Dysfunction Associated Fatty Liver Disease in Long-Term Cholecystectomy Patiens
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 主要终点
- Incidence and severity of metabolic dysfunction-associated fatty liver disease (MAFLD) in patients after long term follow up post cholecystectomy
研究概览
简要总结
This observational study aims to evaluate the association between long-term cholecystectomy and the development of metabolic dysfunction-associated fatty liver disease (MAFLD) in adult patients. The study will assess the prevalence and severity of hepatic steatosis in individuals who underwent cholecystectomy several years earlier and compare clinical, metabolic, and biochemical parameters to identify potential risk factors. The goal is to determine whether cholecystectomy contributes to metabolic alterations that increase the likelihood of MAFLD in the long term.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Patients less than 18 years old.
- •Body mass index (BMI) ≤ 25 kg/m2
- •Patients with chronic renal failure.
- •Patients with liver cirrhosis.
- •Patients with acute liver dysfunction.
- •Breast feeding and pregnancy.
- •patients have done cholecystectomy less than 5 years ago.
结局指标
主要结局
Incidence and severity of metabolic dysfunction-associated fatty liver disease (MAFLD) in patients after long term follow up post cholecystectomy
时间窗: 5 years post-cholecystectomy
次要结局
- Changes in serum level of ALT in post-cholecystectomy patients(Annually for 5 years)
研究者
Yasmeen Ahmed Farrag Ahmed
Resident Doctor Tropical Medicine and Gastroenterology
Sohag University