ACTRN12611000832976尚未招募未知
Minor Salivary Gland Transplantation for subjective improvement of dry eye disease and objective reduction of ocular inflammation associated with dry eye disease in patients with Severe Dry Eye Disease and healthy individuals
Dinesh Selva0 个研究点目标入组 10 人开始时间: 2011年8月8日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •All patients with severe DED defined by OSDI score and stage 4 dry eye severity grading scheme
- •Persistant severe pain and symptoms
- •Marked conjunctival staining
- •Severe corneal erosions
- •Flourescein tear break up time immediate (TBUT)
- •Schirmer score <2
- •Inclusion for healthy control group:
- •Clinically no evidence of dry eye disease
- •Able to attend the follow-up appointments
排除标准
- •Age <18 years old
- •Inability to provide consent
- •Previous gland graft
- •Existing ocular disease
- •Subjects using topical or systemic medications for allergies
- •Contact lens wearers
- •Exclusion criteria for control group:
- •Inability to provide consent
- •Existing ocular disease
- •Subjects using topical or systemic medications for allergies
- •Contact lens wearers
研究者
相似试验
招募中
不适用
Autologous Transplantation of Adult Salivary Gland Stem Cells to Restore Submandibular Gland Function after RadiotherapyNL-OMON49128niversitair Medisch Centrum Groningen18
Unknown
不适用
Minor Salivary Gland Transplantation for Cicatrizing ConjunctivitisCicatrizing ConjunctivitisStevens-Johnson Syndrome Toxic Epidermal Necrolysis SpectrumMucous Membrane PemphigoidChronic Graft Versus Host DiseaseSjogren SyndromeChemical Burn to EyeNCT03839069National Taiwan University Hospital30
已完成
不适用
Removal of growth on black portion of eye ball by different methodsCTRI/2017/12/010945Armed Forces Medical College74
已完成
不适用
Salivary Gland Transplantation in the Treatment of Dry Eye in Patients With Stevens-Johnson Syndrome.SymblepharonOcular Surface DiseaseTransplantationDry EyeNCT01178242Federal University of São Paulo19
已完成
不适用
Transcutaneous Submandibular Gland Biopsy: Feasibility of Repeat Biopsy as a Progression Marker for Parkinson's DiseaseParkinson DiseaseNCT03359226Mayo Clinic7