The Effect of an Aerobic Exercise Programme in Stroke Patients
Phase 3
- Conditions
- Cerebrovascular Accident
- Interventions
- Behavioral: Follow-up control groupBehavioral: Follow-up second aerobic exercise groupBehavioral: Aerobic exercise groupBehavioral: Control groupBehavioral: Follow-up first aerobic exercise group
- Registration Number
- NCT01070459
- Lead Sponsor
- University College of Antwerp
- Brief Summary
This study aims to investigate the effect of aerobic exercise on the aerobic capacity, the daily functioning, post-stroke fatigue , depression and cardiovascular risk factors in stroke patients.
- Detailed Description
People with neurologic impairments after stroke often show decreased aerobic exercise capacity. The etiologies of which are assigned to physiologic changes in paretic muscle, gait deficits and disability-related deconditioning. This declares that stroke patients live an inactive lifestyle and therefore stay cardiovascular risk patients.
The usefulness of aerobic training on aerobic capacity is recently been proved in clinical stroke research. However, no study can shown the long-term effect of aerobic exercises. Also the effect of aerobic exercises on daily functioning, fatigue and depression in stroke needs to be established.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- First CVA according to the WHO definition (A primary, first ever stroke ash revealed by rapidly developing clinical signs or focal or global disturbance or cerebral function, with symptoms lasting 24 hours or longer or leading to death, with no apparent cause other than or vascular origin.) This includes ischemic infarct or an intracerebral haemorrhage
- The offense can be maximum 3 up to 6 weeks after onset
- Patient must be able to follow simple verbal instructions
- To cycle during 1 minute at 20 Watt, 50RPM,
- Cardiac stable
Exclusion Criteria
- Have another neurological impairments with permanent damage such as former cranial trauma, multiple sclerosis, epileptic status... which already present were for current CVA
- Having on CVA resembling symptoms as a result of subdural haemorrhage, a tumour, encephalitis or a trauma
- Barthel index < 50 before the stroke onset
- Age > 80 year
- No authorisation form of the patient or of the family
- Absolute contra-indications for effort test (ACC/AHA guidelines)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Control group Follow-up control group The patients continue their regular therapy in the rehabilitation center. They participate in a 12-week programme of passive mobilisation of the hemiplegic knee, using a continuous passive motion device. Patients will be trained three times a week, 30 minutes/session. Follow-up second aerobic exercise group Follow-up second aerobic exercise group - Aerobic exercise group Aerobic exercise group The patients continues their regular therapy in the rehabilitation center. They participate in a 12-week programme of aerobic training 30 minutes/session, using a leg cycle bike. Patients will be trained three times a week. The heart rate will vary from 50 tot 75% of their predicted heart rate. Each patient will be provided with an progressive exercise prescription based on 50-75% of their predicted maximum heartrate. Throughout the training sessions the heart rate will be monitored continuously with a polar pulse rate. Within these 12 week training programme 4 information sessions will be offered to patients and relatives about risk factors of stroke, usefulness of an active lifestyle and healthy eating. Aerobic exercise group Follow-up first aerobic exercise group The patients continues their regular therapy in the rehabilitation center. They participate in a 12-week programme of aerobic training 30 minutes/session, using a leg cycle bike. Patients will be trained three times a week. The heart rate will vary from 50 tot 75% of their predicted heart rate. Each patient will be provided with an progressive exercise prescription based on 50-75% of their predicted maximum heartrate. Throughout the training sessions the heart rate will be monitored continuously with a polar pulse rate. Within these 12 week training programme 4 information sessions will be offered to patients and relatives about risk factors of stroke, usefulness of an active lifestyle and healthy eating. Aerobic exercise group Follow-up second aerobic exercise group The patients continues their regular therapy in the rehabilitation center. They participate in a 12-week programme of aerobic training 30 minutes/session, using a leg cycle bike. Patients will be trained three times a week. The heart rate will vary from 50 tot 75% of their predicted heart rate. Each patient will be provided with an progressive exercise prescription based on 50-75% of their predicted maximum heartrate. Throughout the training sessions the heart rate will be monitored continuously with a polar pulse rate. Within these 12 week training programme 4 information sessions will be offered to patients and relatives about risk factors of stroke, usefulness of an active lifestyle and healthy eating. Follow-up first aerobic exercise group Follow-up first aerobic exercise group - Follow-up control group Control group - Follow-up control group Follow-up control group -
- Primary Outcome Measures
Name Time Method VO2-peak, strength, walking, activities of daily living baseline , after 12 weeks training. Follow-up measurements after 6 months, 1 and 2 years after baseline.
- Secondary Outcome Measures
Name Time Method post-stroke fatigue, depression, lifestyle, cardiovascular risk factors baseline , after 12 weeks training. Follow-up measurements after 6 months, 1 and 2 years after baseline.
Trial Locations
- Locations (1)
Revalidatiecentrum Sint-Ursula
🇧🇪Herk-de-Stad, Limburg, Belgium