NCT01032109已完成不适用
Verteporfin Photodynamic Therapy Alone Versus Combined With Intravitreal Bevacizumab for Neovascular Age-related Macular Degeneration
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Visual acuity
研究概览
简要总结
The purpose of this study is to compare 12-month results of two single initial treatments-photodynamic therapy with verteporfin alone and this therapy combined with intravitreal bevacizumab-for neovascular age-related macular degeneration, not including patients with polypoidal choroidal vasculopathy who were presumed to have age-related macular degeneration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •choroidal neovascularization caused by age-related macula degeneration
- •no previous treatment
- •a follow-up at least 12 months
- •a baseline visual acuity ranging from a letter score of 0 to 70 on the Early Treatment Diabetic Retinopathy Study chart
排除标准
- •choroidal neovascularization caused by other eye diseases
- •ocular surgery within the past 3 mouths
- •history of uveitis
- •intraocular pressure higher than 25 mmHg, or glaucoma
- •history of systemic or ocular thromboembolic events.
研究组 & 干预措施
Bevacizumab
Experimental
干预措施: Bevacizumab (Drug)
结局指标
主要结局
Visual acuity
时间窗: The comparison between baseline and 12-month
次要结局
未报告次要终点
研究者
Takahiro Kawaji
Associate Professor
Kumamoto University
研究点 (1)
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