Surgical outcomes following breast reconstruction in patients with and without a history of chest radiotherapy for Hodgkin lymphoma: a multicenter, matched cohort study

Department of Plastic and Reconstructive Surgery, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands0 sites191 target enrollmentJuly 15, 2022

ConditionsZ42.1 C81 Follow-up care involving plastic surgery of breast Hodgkin lymphoma

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Z42.1
Sponsor: Department of Plastic and Reconstructive Surgery, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands
Enrollment: 191
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

No summary available.

Registry

who.int

Start Date

July 15, 2022

End Date

July 15, 2022

Last Updated

last year

Study Type

Observational

Sex

Female

Investigators

Sponsor

Department of Plastic and Reconstructive Surgery, Erasmus MC Cancer Institute, University Medical Centre Rotterdam, Rotterdam, The Netherlands

Eligibility Criteria

Inclusion Criteria

•Breast reconstructions in Hodgkin survivors diagnosed with BC after previous chest radiotherapy for Hodgkin and who had undergone BR after therapeutic or prophylactic mastectomy.
•Control breast reconstructions after therapeutic or prophylactic mastectomy in patients without a history of HL or chest radiotherapy were matched to patients in group 1 on age at mastectomy (±five years), date of BR (±five years), and type of BR (direct\-to\-implant; tissue expander/implant; autologous with implant; autologous only) and timing of BR (immediate or delayed).

Exclusion Criteria

•Breasts which had received radiotherapy for BC before BR were excluded. Patients were excluded if their electronic health records had missing data regarding supradiaphragmatic radiotherapy.