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临床试验/NCT03346746
NCT03346746
已完成
不适用

Utilizing GI: Exploring an Optimum Glycaemic Profile for Cognitive Function Across the Day in Healthy Individuals

Matthew Grout1 个研究点 分布在 1 个国家目标入组 40 人2017年2月1日

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Cognitive Performance
发起方
Matthew Grout
入组人数
40
试验地点
1
主要终点
Change in cognitive performance between time points assessed
状态
已完成
最后更新
8年前

概览

简要总结

This study provides participants with two diets that vary in their glycaemic index values (low vs. high), whilst also measuring cognitive performance and mood.

详细描述

Therefore, the current study introduces cognitive testing into study procedures. Participants will consume the favourable and unfavourable conditions (each containing three meals) on separate days following a crossover, randomised, couterbalanced design. The primary dependent variable is cognitive function, whilst secondary measures include glucose and mood. It is hypothesised that the favourable meal profile will be associated with cognitive and physiological benefits relative to the unfavourable meal profile.

注册库
clinicaltrials.gov
开始日期
2017年2月1日
结束日期
2017年8月30日
最后更新
8年前
研究类型
Interventional
研究设计
Crossover
性别
All

研究者

发起方
Matthew Grout
责任方
Sponsor Investigator
主要研究者

Matthew Grout

Doctoral Researcher

University of Reading

入排标准

入选标准

  • Aged between 18 and 25 years of age
  • Willing to participate in the entire study (signed informed consent required)
  • Male or female (not pregnant)

排除标准

  • Suffer from diabetes
  • Are anaemic
  • Have any food intolerances or allergies
  • History of alcohol or drug misuse
  • Diagnosed with any of the following;
  • High blood cholesterol
  • High blood pressure
  • Thyroid disorder
  • Heart problems, stroke or any vascular disease in the past 12 months
  • Inflammatory diseases such as rheumatoid arthritis

结局指标

主要结局

Change in cognitive performance between time points assessed

时间窗: This was tested 9 times a day, with two days, giving a total of 18 times. Each battery of four tasks lasted approximately 15 minutes

A participants performance over four cognitive tasks

次要结局

  • Glycaemic profile(This was measured 23 times a day, for two days, giving a total of 46 times)
  • Sleepiness(This takes approximately 30 seconds to complete. Participants were tested six times a day. There were two test days. Giving a total of 12 times, or approximately 6 minutes overall.)
  • Fullness(This takes approximately 30 seconds to complete. Participants were tested six times a day. There were two test days. Giving a total of 12 times, or approximately 6 minutes overall.)
  • Mood (alertness, anxiety and contentment) using the Bond-Lader (1974) Visual Analogue Scale(This takes approximately 5 minutes to complete. Participants were tested six times a day. There were two test days. Giving a total of 12 times, or approximately 60 minutes of mood scale completion.)
  • Hunger(This takes approximately 30 seconds to complete. Participants were tested six times a day. There were two test days. Giving a total of 12 times, or approximately 6 minutes overall.)

研究点 (1)

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