Japanese Multicenter Evaluation of LOng- versus short-acting Diuretics In Congestive heart failure - J-MELODIC

The J-MELODIC Program Committee0 个研究点目标入组 300 人开始时间: 2006年11月24日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1. Diabetes mellitus that has not been well controlled (fasting blood glucose > 200 mg/dl, HbA1c > 9%) 2. Current symptomatic hypotension 3. Hypertension that has not been controlled to the satisfaction of the investigator 4. Serum creatinine > 2.5 mg/dl 5. Serious liver disease 6. Acute coronary syndrome 7. Any life-threatening acute disease (including patients with implantable cardiac defibrillator) 8. Hemodynamically significant (in the investigators opinion) LV outflow tract obstruction (due to either aortic stenosis or ventricular hypertrophy) 9. Chronic obstructive pulmonary disease or restrictive lung disease 10. Primary pulmonary hypertension or pulmonary hypertension not due to LV dysfunction 11. Acute myocardial infarction or cerebrovascular accident within the last 3 months 12. Percutaneous coronary intervention or open heart surgery within the last 3 months 13. Any change in cardiovascular drug therapy within a month prior to randomization 14. Malignancy 15. Surgery for resecting malignant tumor within 5 years 16. Patients unable to walk without personal aid 17. Serious cerebrovascular disease 18. Patients who require intravenous inotropes 19. Pregnancy 20. Patients who were judged not to be suitable for entry by physicians

发起方

The J-MELODIC Program Committee