Treatment of COVID-19-induced cytokine storm by hemoperfusio

Phase 2

Recruiting

Conditions: Condition 1: COVID-19. Condition 2: COVID-19-induced pneumonia.
COVID-19, virus identified
Pneumonia due to SARS-associated coronavirus
U07.1
J12.81

Registration Number: IRCT20200317046797N5

Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 10

Inclusion Criteria

Positive PCR for COVID-19
PaO2/FiO2 less than 200 mmHg
More than 50% involvement of pulmonary fields in CT scan
Respiratory rate more than 30/minute
Resting O2 saturation less than 90%

Exclusion Criteria

Coagulation abnormality
Plasma platelets count <30000/µL
Other viral infection and bacterial sepsis
Advanced multi-organ failure

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The general condition of the patient. Timepoint: Before intervention and 1 day after final intervention. Method of measurement: Lung CT scan; No need to receive any intensive respiratory care in the patient.;Mortality rate. Timepoint: At baseline and discharge time or patient death. Method of measurement: Observation.;Need for intubation. Timepoint: Period of hospitalization. Method of measurement: Observation or reading of hospitalized documents.;Period of hospitalization. Timepoint: At baseline and discharge time. Method of measurement: Number of hospitalized days.

Secondary Outcome Measures