Randomized Trial on Adjuvant Chemotherapy in Colon Carcinoma Dukes B
- Conditions
- Colon Cancer Stage II
- Registration Number
- NCT00309543
- Lead Sponsor
- Austrian Breast & Colorectal Cancer Study Group
- Brief Summary
This clinical investigation examined the influence of cytostatic chemotherapy with 5-fluorouracil, modulated by biologically active leucovorin, on patients' survival time following surgery for colon carcinoma Stage II.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 636
- Patients with histologically verified, operable colon carcinoma Stage II (RO, T3-4, N0, M0)
- Age: less than 80 years
- WHO Performance > 2
- Adequate bone marrow reserve, renal and hepatic functions
- Informed consent
- Rectal cancer
- R1or R2 resection; carcinosis peritonei
- Start of treatment > 42 days postop; other adjuvant radiotherapy, chemotherapy or immunotherapy
- Serious concomitant disease, in particular chronically inflammatory large intestine, cardiopathic or metabolic disease, malignant second carcinoma
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Overall survival
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (18)
Hospital Guessing
🇦🇹Guessing, Burgenland, Austria
Hospital Oberpullendorf
🇦🇹Oberpullendorf, Burgenland, Austria
Hospital BHB St. Veit/Glan, Surgery
🇦🇹St. Veit a. d. Glan, Carinthia, Austria
State Hospital Wolfsberg
🇦🇹Wolfsberg, Carinthia, Austria
Hospital Hainburg
🇦🇹Hainburg, Lower Austria, Austria
Hospital Krems
🇦🇹Krems, Lower Austria, Austria
Hospital Tulln
🇦🇹Tulln, Lower Austria, Austria
Hospital Waidhofen/Thaya
🇦🇹Waidhofen a. d. Thaya, Lower Austria, Austria
Hospital Wiener Neustadt, Surgery
🇦🇹Wiener Neustadt, Lower Austria, Austria
Medical University of Graz, Oncology
🇦🇹Graz, Styria, Austria
Scroll for more (8 remaining)Hospital Guessing🇦🇹Guessing, Burgenland, Austria