Focused Ultrasound Thalamotomy for Tremor Relief in Atypical Parkinsonism

Completed

• Conditions: Dementia With Lewy Bodies; Multiple System Atrophy, MSA; Atypical Parkinsonism

• Registration Number: NCT06204575
• Lead Sponsor: Rambam Health Care Campus

Brief Summary

The goal of this retrospective observational study is to describe the efficacy of focused ultrasound ventral-intermediate nucleus thalamotomy in patients with atypical parkinsonism.

* Is this treatment efficacious in patients with multiple system atrophy?

* Is this treatment efficacious in patients with diffuse Lewy Body Dementia? Data will be collected from patients charts.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-11-01
• Primary Completion: 2023-05-31
• Study Completion: 2023-05-31
• Study First Submitted: 2023-12-31
• Status Verified: 2024-01
• Study First Submitted QC: 2024-01-11
• Last Update Submitted: 2024-01-11
• Study First Posted: 2024-01-12
• Last Update Posted: 2024-01-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

Not provided

Exclusion Criteria

• Patients that did not underwent FUS ventral-intermediate nucleus thalamotomy
• Patients that underwent FUS ventral-intermediate nucleus thalamotomy and do not suffer from MSA or DLBD

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical Rating Scale for Tremor	baseline, pre-procedure, 1 month, 6 months and 1 year following procedure	tremor assessment by Clinical Rating Scale for Tremor. Scores ranging from 0 to 156, with higher scores indicating more severe tremor.

Trial Locations

Locations (1)

Rambam Health Care Campus; 🇮🇱 Haifa, Israel