Pilot Study to Evaluate the Efficacy of Topical Application of Kadali Kshara on Inferior Turbinate Hypertrophy

The patient diagnosed with inferior turbinate hypertrophy fulfilling inclusion and exclusion criteria attending OPD Shalakya tantra and ENT OPD, S.S.Hospital ,IMS BHU will be assigned into control and trial group by simple randomization. Present pilot study sample size is 15 in trial group and 10 in control group. In the trial group, topical application of kadali kshara was done while in the control group nasal decongestants Xylometazoline oxymetazoline hydrochloride nasal solution was given for 5 days.The patient will be assessed based on subjective and objective parameters and follow up for 7th and 15th day. Subjective parameters will be assessed according to NOSE(Nasal obstruction symptom evaluation) scores - Nasal congestion or stuffiness, Nasal blockage or obstruction, trouble breathing my nose, Unable to get enough air through my nose during exercise or exertion, Trouble sleeping, just before commencing treatment , after treatment and during follow up. Objective parameters include Friedman grading system of inferior turbinate hypertrophy, Nasal endoscopic grading system of inferior turbinate hypertrophy, Laboratory test CBC and ESR and Pictorial presentation of inferior turbinate hypertrophy before treatment and after treatment, assessed on before and after treatment. The data collected will be analysed statistically by using appropriate test.