A randomised controlled trial and economic evaluation of a community-based physical activity intervention to prevent mobility-related disability for retired older people: the REACT (REtirement in ACTion) trial
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Specialty: Primary Care, Primary sub-specialty: Ageing
- Sponsor
- niversity of Bath
- Enrollment
- 777
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
2018 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/29665854 protocol 2022 Results article in https://doi.org/10.1016/S2468-2667(22)00004-4 (added 22/03/2022) 2022 Results article in https://doi.org/10.1016/S2468-2667(22)00030-5 Cost-effectiveness (added 22/03/2022) 2023 Results article in https://doi.org/10.1186/s12966-023-01434-0 Qualitative results (added 27/04/2023) 2023 Other publications in https://pubmed.ncbi.nlm.nih.gov/37299849/ Validation of the pfSTEP digital biomarker (added 11/07/2024) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/35361556/ MRI sub study results (added 11/07/2024) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35658857/ delivery fidelity of the intervention part of the process eveluation (added 11/07/2024) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37575112/ long-term functionality (added 11/07/2024)
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Retired men and women aged 65 or older
- •2\. Plan to reside in the target area (Bath/Bristol, Devon, Birmingham) for at least 24 months
- •3\. Score 48 (inclusive) on the Short Physical Performance Battery (SPPB)
Exclusion Criteria
- •1\. A documented or patient reported medical condition that would preclude participation, including:
- •1\.1\. Arthritis so severe it would prevent participation in physical activity
- •1\.2\. Parkinson’s disease
- •1\.3\. Dementia
- •1\.4\. Lung disease requiring use of corticosteroids or supplemental oxygen
- •1\.5\. Severe kidney disease that requires dialysis
- •1\.6\. Severe heart disease that would prevent participation in physical activity (for example chest pain when walking one or two hundred yards or up a flight of stairs)
- •1\.7\. An implanted cardiac defibrillator, a cardiac arrest which required resuscitation
- •1\.8\. Severe uncontrolled psychiatric illness
- •1\.9\. Currently receiving radiation therapy or chemotherapy treatment for cancer
Outcomes
Primary Outcomes
Not specified