Clinical and Radiographic Assessment of I-PRF Versus Nano Mineral Trioxide Aggregate Combined with I-PRF Scaffold in Vital Pulp Therapy in Mandibular First Molars with Closed Apices: "Randomized Controlled Trial"
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- Post operative pain assessments
研究概览
简要总结
Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF in pulpotomy in mature Mandibular First Molars
详细描述
Clinical and Radiographic Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF Scaffold in Vital Pulp Therapy in Mandibular First Molars with Closed Apices: "Randomized Controlled Trial"
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 15 Years 至 30 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients suffering from Symptomatic irreversible pulpitis in mature mandibular molars only will be involved.
- •Patients of either gender aged from 15-
- •Tooth should give positive response to cold test.
- •The tooth is restorable
- •Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
- •Patients who will agree to the consent and will commit to follow-up period.
- •Patients with mature root.
- •Patients with no internal or external resorption and no periapical lesions.
- •Soft tissues around the tooth are normal with no swelling or sinus tract.
排除标准
- •Patients with immature roots.
- •Haemostasias after 10 minutes can not be controlled after total pulpotomy
- •Patients with periapical lesions or infections.
- •Pregnant females.
- •Patients with fistula or swelling
- •Patients with necrotic pulp.
研究组 & 干预措施
MTA Pulpotomy
using MTA as pulpotomy capping agent in mature permanent teeth
干预措施: pulpotomy (Procedure)
I-PRF pulpotomy
using I-PRF as pulpotomy capping agent in mature permanent teeth
干预措施: pulpotomy (Procedure)
I-PRF combined with Nano MTA pulpotomy
using nano MTA mixed with I-prf as pulpotomy capping agent in mature permanent teeth
干预措施: pulpotomy (Procedure)
结局指标
主要结局
Post operative pain assessments
时间窗: 6 hours post operative , 12 hours post operative , 24h (one day) post operative , 72h (3 days ) post operative and 7 days (one week) post operative
Pain assessments were made postoperatively with numerical rate scale. The scale includes scores from 0 to 10 where 0 indicates no pain , scores 1 to 3 indicates mild pain , scores 4 to 6 indicates moderate and scores 7 to 10 indicates severe pain.
次要结局
- Clinical and radiographic success(1 month post operative ,3 months clinical and radiograph ,6 months clinical and radiograph ,9 months clinical and radiograph and 12 months clinical and radiograph.)
研究者
Abdelrahman Mohamed Elsayed Metwally Omar
Principle investigator
Future University in Egypt