Risk Factors Affecting Morbidity and Mortality in Perforated Peptic Ulcer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 85
- 试验地点
- 1
- 主要终点
- Postoperative Mortality Rate
研究概览
简要总结
Perforation is one of the most severe and life-threatening complications of peptic ulcer disease. This study aims to evaluate the risk factors associated with postoperative morbidity and mortality in patients undergoing surgery for peptic ulcer perforation, with a focus on the timing of presentation, demographic variables, surgical delay, and their association with postoperative outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 15 Years 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with peptic ulcer perforation aged> 15 years and <75 years.
- •Patients with duodenal or gastric perforation of peptic ulcer origin.
- •Patients who underwent simple closure with omental patch as a standard operative procedure.
排除标准
- •Patients treated with conservative management.
- •Patients with perforation of peptic ulcer origin at the jejunum, ileum adjacent to Meckel's diverticulum.
- •Patients presenting with recurrent perforation or stomal ulcer perforation.
结局指标
主要结局
Postoperative Mortality Rate
时间窗: 12 months (from patient enrollment to completion of follow-up)
Incidence of death following surgical intervention for perforated peptic ulcer.
Postoperative Morbidity Rate
时间窗: 12 months (from patient enrollment to completion of follow-up)
Incidence of postoperative complications (e.g., wound infection, sepsis, anastomotic leak, pneumonia) in patients undergoing surgery for perforated peptic ulcer.
次要结局
未报告次要终点
研究者
Prajjwol Luitel
Co-investigator
Maharajgunj Medical Campus