Prophylaxis of Ventilator Associated Pneumonia by Continuous Lateral Rotation Therapy

Not Applicable

Completed

• Conditions: Pneumonia, Ventilator-Associated
• Interventions: Procedure: Continuous lateral rotation therapy

• Registration Number: NCT00529776
• Lead Sponsor: Medical University of Vienna

Brief Summary

Hypothesis: Ventilator associated pneumonia (VAP) in critically ill patients may be prevented by continuous lateral rotation therapy (CLRT) using specially designed, motor driven beds.

Patients are randomized to CLRT or supine position if mechanically ventilated and not suffering from pneumonia or ARDS within 48 hours after intubation. Prophylaxis of VAP is standardized in both groups. Primary endpoint is incidence of VAP, secondary endpoints are length of ventilation, length of stay and mortality.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09
• Study First Submitted: 2007-09-12
• Study First Submitted QC: 2007-09-12
• Study First Posted: 2007-09-14
• Study Completion: 2008-05
• Status Verified: 2008-06
• Last Update Submitted: 2008-06-10
• Last Update Posted: 2008-06-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Mechanically ventilated
• Intubated not longer than 48 h
• Medical cause for ICU admission
• Expected to be ventilated for > 48 hours

Exclusion Criteria

• Pneumonia or ARDS present
• Postoperative patient

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Continuous lateral rotation therapy	Continuous lateral rotation therapy

Primary Outcome Measures

Name	Time	Method
Ventilator associated pneumonia

Secondary Outcome Measures

Name	Time	Method
Length of hospital stay
ICU and hospital Mortality
Length of mechanical ventilation

Trial Locations

Locations (1)

Vienna General Hospital, Medical University of Vienna; 🇦🇹 Vienna, Austria