Light Exposure Tracker in Alzheimer's Disease.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Saliva samples for melatonin levels
Study Overview
Brief Summary
The purpose of this research study is to investigate the relationship between reminder messages sent via text and compliance with a daily morning light intervention designed to advance the circadian clock. Twenty healthy adults will be recruited to participate in a randomized, cross-over study where daily messages are, or are not, provided to remind participants to carry out the intervention.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 55 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •healthy adults over the age of 55
- •score of 25 or greater on MoCA
Exclusion Criteria
- •Severe sleep apnea
- •restless leg syndrome
- •obstructing cataracts
- •macular degeneration
- •diabetic retinopathy
- •use of sleep medications
- •brain disease
Arms & Interventions
Light Googles plus reminder text messages
Participants use green light goggles for one hour each morning for two consecutive weeks and also receive a daily text message reminding them to wear the light goggles
Intervention: Light goggles (Device)
Light Googles plus reminder text messages
Participants use green light goggles for one hour each morning for two consecutive weeks and also receive a daily text message reminding them to wear the light goggles
Intervention: Daily reminder test message (Behavioral)
Light Goggles alone
Participants use green light goggles for one hour each morning for two consecutive weeks
Intervention: Light goggles (Device)
Outcomes
Primary Outcomes
Saliva samples for melatonin levels
Time Frame: Baseline and 2-weeks post-intervention for each Arm
Serial saliva samples will be collected to calculate dim light melatonin onset.
Secondary Outcomes
- Light exposure using the Speck(worn all 12 study weeks)
- Sleep time using actigraphy(worn all 12 study weeks)
Investigators
Mariana Figueiro
Professor
Icahn School of Medicine at Mount Sinai