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临床试验/NCT07765017
NCT07765017尚未招募不适用

Association Between Early Mobilization and Prolonged Intensive Care Unit Stay in Postoperative Patients: A Prospective Observational Study

Ankara Training and Research Hospital0 个研究点目标入组 80 人开始时间: 2026年10月15日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
80
主要终点
Prolonged Intensive Care Unit Stay

研究概览

简要总结

This prospective observational cohort study aims to evaluate early mobilization in adult postoperative patients admitted to the intensive care unit (ICU) and to investigate its association with short-term clinical outcomes. Early meaningful mobilization is defined as achieving at least sitting at the edge of the bed (mobilization level ≥4) within the first 24 hours after ICU admission. Patients will be classified according to whether early meaningful mobilization is achieved. The primary objective is to evaluate the association between early meaningful mobilization and prolonged ICU stay. Secondary outcomes include mechanical ventilation requirement and duration, hospital length of stay, need for reintubation, development of delirium, complications occurring during mobilization, and ICU mortality.

详细描述

This is a prospective observational cohort study involving adult postoperative patients admitted to the intensive care unit (ICU). The study aims to systematically evaluate early mobilization practices and investigate the association between early mobilization and short-term clinical outcomes in postoperative ICU patients.

Mobilization performed within the first 24 hours after ICU admission will be evaluated according to predefined standardized criteria. Mobilization levels will be recorded using a scale ranging from passive movements to independent mobilization. Early meaningful mobilization is defined as achieving at least sitting at the edge of the bed (mobilization level ≥4) within the first 24 hours after ICU admission. Patients will be classified according to whether early meaningful mobilization is achieved.

The primary objective is to evaluate the association between early meaningful mobilization and prolonged ICU stay. Secondary objectives include evaluating its association with the requirement for and duration of mechanical ventilation, hospital length of stay, need for reintubation, development of delirium, complications occurring during mobilization, ICU mortality, and other early clinical outcomes.

Clinical factors potentially associated with the feasibility of early mobilization will also be evaluated. These include age, comorbidities, preoperative functional capacity, type and duration of surgery, APACHE II and SOFA scores at ICU admission, requirement for mechanical ventilation, vasopressor support, and sedation level. In patients who are not mobilized early, potential barriers to mobilization, including hemodynamic instability, respiratory insufficiency, deep sedation, pain, surgical restrictions, and organizational factors, will be recorded.

Patients will be followed throughout their ICU and hospital stay, and relevant clinical outcomes will be recorded. Demographic characteristics, surgical data, clinical parameters at ICU admission, mobilization status, and clinical outcomes will be collected using a standardized data collection form. All collected data will be anonymized for analysis.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age 18 years or older
  • •Admission to the intensive care unit for postoperative care
  • •ICU stay of at least 24 hours
  • •Ability to assess the patient's mobilization level within the first 24 hours following ICU admission
  • •Provision of informed consent for participation in the study

排除标准

  • •Age under 18 years
  • •Pregnancy
  • •Death within the first 24 hours after ICU admission
  • •Clinical conditions contraindicating mobilization, including active massive bleeding, significant hemodynamic instability, unstable fracture, open abdomen, or similar conditions

研究组 & 干预措施

Early Meaningful Mobilization

Postoperative ICU patients who achieve a mobilization level of ≥4 within the first 24 hours after ICU admission.

No Early Meaningful Mobilization

Postoperative ICU patients who do not achieve a mobilization level of ≥4 within the first 24 hours after ICU admission.

结局指标

主要结局

Prolonged Intensive Care Unit Stay

时间窗: Through ICU stay, an expected average of 3 days

Prolonged ICU stay will be evaluated according to the duration of ICU hospitalization and compared between patients who achieve early meaningful mobilization and those who do not. Early meaningful mobilization is defined as achieving a mobilization level of ≥4 within the first 24 hours after ICU admission.

次要结局

  • ICU Mortality(Through ICU stay, an expected average of 3 days)
  • Mechanical Ventilation Requirement(Through ICU stay, an expected average of 3 days)
  • Duration of Mechanical Ventilation(Through ICU stay, an expected average of 3 days)
  • Hospital Length of Stay(Through hospitalization, an expected average of 7 days)
  • Reintubation Requirement(Through ICU stay, an expected average of 3 days)

研究者

发起方
Ankara Training and Research Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Dilek Kuzukiran Kocatas

Principal Investigator

Ankara Training and Research Hospital

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