Pilot Study: Collection of Urine From Sanitary Napkins for the Analysis of Micronutrient Deficiencies
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Focus: Nutritional Deficiency
- Sponsor
- University of Hohenheim
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Correlation untreated and expressed urine
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
This study aims to find an easy urinary collection method for the assessment of urinary markers of micronutrient status.
Detailed Description
Urinary collection in newborns and infants can be difficult. Our study aims to find an easy and cheap alternative to urinary collection bags and specialized pads that can be used to measure biomarkers of iodine and vitamin B12 status in urine and can be employed in large scale trials. Using correlation analyses, the association of urinary iodine and methylmalonic acid from healthy volunteers will be assessed between untreated sample and a sample expressed from a sanitary napkin. Participants will be recruited based on their dietary pattern (omnivorous, vegetarian and vegans) to have a broad spectrum of analyte concentration. Participants weight, height, age, nutritional supplement use and diet will be assessed.
Investigators
Maren Podszun
Dr. rer. nat. Maren Podszun
University of Hohenheim
Eligibility Criteria
Inclusion Criteria
- •Healthy volunteers Written informed consent
Exclusion Criteria
- •BMI \< 18,5 and \>24,9 Use of medication (except contraceptives) Smoking
Outcomes
Primary Outcomes
Correlation untreated and expressed urine
Time Frame: 8-9 weeks after completion
Correlation of creatinine, methylmalonic acid and iodine between unprocessed urine and urine expressed from a sanitary diaper to evaluate possible matrix effects on analytes.
Secondary Outcomes
- Correlation of urinary biomarkers with food and supplement intake(8-9 weeks after completion)