Retrospective Dosimetric Study of Prone Radiotherapy for Breast Cancer
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 280
- 试验地点
- 1
- 主要终点
- Radiation dose to heart and lungs
研究概览
简要总结
The study purpose is to evaluate whether or not clinical characteristics of women with breast cancer can predict which position for radiation treatment, prone or supine, will be associated with a dosimetry gain. Dosimetry gain in this study means the lowest radiation dose to non-target organs (heart, lungs, contralateral breast), while giving the prescribed dose to tumor bed and ipsilateral breast.
详细描述
Retrospectively identify women who received curative radiation treatment after breast conserving cancer surgery, in whom simulation in prone and in supine position was performed. Compare the treatment plans for doses to targets and to non-target organs, according to clinical parameters of body mass index, size of breast, location of tumor and side. Furthermore, evaluate whether a single CT slide is enough or not to predict a dosimetry advantage.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Breast conserving surgery
- •Adjuvant radiation treatment
- •Simulation done prone and supine
排除标准
- •Simulation in only one position
结局指标
主要结局
Radiation dose to heart and lungs
时间窗: 4 months
Computations of doses and verification of physics charts.
次要结局
- Radiation dose to tumor bed and ipsilateral breast(4 months)
研究者
Vincent Vinh-Hung
MD, PhD
University Hospital, Geneva