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Clinical Trials/NCT02237469
NCT02237469
Active, Not Recruiting
N/A

Retrospective Dosimetric Study of Prone Radiotherapy for Breast Cancer

Vincent Vinh-Hung1 site in 1 country280 target enrollmentSeptember 2010

Overview

Phase
N/A
Intervention
Not specified
Conditions
Breast Cancer Female
Sponsor
Vincent Vinh-Hung
Enrollment
280
Locations
1
Primary Endpoint
Radiation dose to heart and lungs
Status
Active, Not Recruiting
Last Updated
3 years ago

Overview

Brief Summary

The study purpose is to evaluate whether or not clinical characteristics of women with breast cancer can predict which position for radiation treatment, prone or supine, will be associated with a dosimetry gain. Dosimetry gain in this study means the lowest radiation dose to non-target organs (heart, lungs, contralateral breast), while giving the prescribed dose to tumor bed and ipsilateral breast.

Detailed Description

Retrospectively identify women who received curative radiation treatment after breast conserving cancer surgery, in whom simulation in prone and in supine position was performed. Compare the treatment plans for doses to targets and to non-target organs, according to clinical parameters of body mass index, size of breast, location of tumor and side. Furthermore, evaluate whether a single CT slide is enough or not to predict a dosimetry advantage.

Registry
clinicaltrials.gov
Start Date
September 2010
End Date
December 2023
Last Updated
3 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Vincent Vinh-Hung
Responsible Party
Sponsor Investigator
Principal Investigator

Vincent Vinh-Hung

MD, PhD

University Hospital, Geneva

Eligibility Criteria

Inclusion Criteria

  • Breast conserving surgery
  • Adjuvant radiation treatment
  • Simulation done prone and supine

Exclusion Criteria

  • Simulation in only one position

Outcomes

Primary Outcomes

Radiation dose to heart and lungs

Time Frame: 4 months

Computations of doses and verification of physics charts.

Secondary Outcomes

  • Radiation dose to tumor bed and ipsilateral breast(4 months)

Study Sites (1)

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