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Thickness of Retinal Layers in Amblyopia

Completed
Conditions
Amblyopia
Interventions
Other: Optical coherence tomography
Registration Number
NCT01179763
Lead Sponsor
Samsung Medical Center
Brief Summary

The purpose of this study is to examine retinal layer thickness in amblyopia.

Detailed Description

Amblyopia is a visual disorder characterized by a reduction of vision that cannot be immediately improved by refractive correction or accounted for by clinically determined anatomic defects of the eye or visual pathway. Evidence for direct retinal changes in eyes with amblyopia has been controversial. It has been hypothesized that amblyopia may affect the postnatal maturation of the retina including the postnatal reduction of retinal ganglion cells. However, although some studies have found incrased retinal nerve fiber layer thickness in amblyopic eyes, others have found no significant differences. This sutdy will examine the retinal layer thickness in amblyopia and compare the retinal layer thickness between amblyopic eyes and nonamblyopic fellow eyes.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
22
Inclusion Criteria
  • Amblyopia
Exclusion Criteria
  • Other retinal disease
  • Anisometropia
  • Neurologic abnormalities

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Retinal layer thickness analysisOptical coherence tomographyOptical coherence tomography will be conducted to analyze retinal layer thickness (safe examination)
Primary Outcome Measures
NameTimeMethod
Retinal layer thicknessOne month

Optical coherence tomography scan will be conducted to analyze retinal layer thickness, when the patient are enrolled.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Samsung Medical Center

🇰🇷

Seoul, Korea, Republic of

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