Treating Violence-related PTSD and Substance Risk in Low-income, Urban Adolescents

Not Applicable

Completed

• Conditions: Posttraumatic Stress Disorder; Substance Use Disorders
• Interventions: Behavioral: Narrative Exposure Therapy

• Registration Number: NCT03737383
• Lead Sponsor: State University of New York at Buffalo

Brief Summary

This project will provide initial feasibility and efficacy data for the implementation of Narrative Exposure Therapy (NET) to urban, at-risk youth. Posttraumatic stress and substance use outcomes, as well as participant responses to the intervention, will be examined.

Detailed Description

The goal of the proposed study is to gather preliminary feasibility and efficacy data for an innovative intervention (Narrative Exposure Therapy: NET) to promote adolescent mental health related to interpersonal trauma (IPT). Among those at highest risk for interpersonal violence and its sequelae are youth from urban, low-resourced neighborhoods. Post-traumatic stress disorder (PTSD) is a common outcome associated with IPT. Substance misuse (SUB) is a frequent concomitant of PTSD. NET is a promising intervention to reduce PTSD symptoms and associated psychological distress, via the supported reconstruction (narrative telling) of the traumas. NET has a critical advantage over existing PTSD treatments in that it can be delivered in a brief format, in community settings where at-risk adolescents are likely to be found. Despite its promise in treating adolescent distress, NET has yet to be tested as an intervention for those who have interpersonal trauma-related PTSD. Further NET's influence on SUB has not been examined.

Accordingly, the objective of this project is to conduct a pilot study (N=30) to estimate NET treatment effects on PTSD symptoms and SUB in IPT-exposed urban adolescents (ages 16-21). Both feasibility and preliminary efficacy data will be collected to serve as pilot work for a larger-scale NIH proposal. Recruitment and intervention will be set within community partners where the adolescents already are connected and are receiving social or psychological services. Outcome data will be collected at: (T0) Baseline, and at 1(T1), and 3 months (T2) follow-up assessments. Participant responses to the intervention will be assessed post-intervention. Change in PTSD, SUB will be estimated with effect sizes and inferential tests. Preliminary evidence of efficacy and feasibility will pave the way for further NET development to offer a patient-oriented, community-based, intervention that will promote adolescent mental health for those at greatest risk for health access and outcomes disparities.

Study Timeline

• Study Start: 2017-12-01
• Study First Submitted: 2018-01-29
• Study First Submitted QC: 2018-11-08
• Study First Posted: 2018-11-09
• Primary Completion: 2021-08-31
• Study Completion: 2021-08-31
• Status Verified: 2023-10
• Last Update Submitted: 2023-10-23
• Last Update Posted: 2023-10-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

• Adolescents (ages 16-25),
• Positive PTSD diagnosis (CAPS diagnosis)
• Positive lifetime incidence of interpersonal violence-related trauma.

Exclusion Criteria

• Actively suicidal with an immediate referral to the community agency crisis staff
• Severe cognitive delay
• Active psychosis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Feasibility and Preliminary Efficacy	Narrative Exposure Therapy	We will be administering Narrative Exposure Therapy to determine participant responses to the intervention, whether the intervention can be delivered successfully in this setting, and preliminary outcomes.

Primary Outcome Measures

Name	Time	Method
Posttraumatic Stress Disorder Checklist-Civilian Version	through study completion, an average of 3 years	assessed via PTSD checklist. The minimum score for this measure is 0 while the maximum is 80. Higher scores indicate more severe PTSD symptoms.

Secondary Outcome Measures

Name	Time	Method
Young Adult Alcohol Consequences Questionnaire (YAACQ)	through study completion, an average of 3 years	alcohol consequences assessed via YAACQ. The minimum score for this measure is 0 while the maximum is 48. Higher scores indicate more alcohol consequences.
Alcohol Use Disorders Identification Test (AUDIT)	through study completion, an average of 3 years	alcohol use assessed via AUDIT. The minimum score for this measure is 0 while the maximum is 40. Higher scores indicate more alcohol use.

Trial Locations

Locations (1)

University at Buffalo Department of Psychology; 🇺🇸 Buffalo, New York, United States