The effectiveness of submucosal administration of methylprednisolone and dexamethasone in comparison to placebo after third molar surgery: a double blinded parallel arm randomized clinical trial

Dr Kinza Ayub0 sites90 target enrollmentOctober 1, 2019

Overview

No summary available.

Registry

who.int

Start Date

October 1, 2019

End Date

TBD

Last Updated

6 years ago

Study Type

Interventional

Sex

All

Sponsor

Dr Kinza Ayub

•Patients in the age group – 20 to 50 years
•Patients with mesioangular impactions Class II position B third molar according to the Pell and Gregory’s classification.
•Patient with no medical conditions

•Patients requiring prophylactic antibiotics before surgical procedure. The following patients will be excluded because taking antibiotic before the treatment will subside the infection and pain and it will act as confounding factor with the study design
•Patients suffering from any mental disorders or with any chronic pain problems. The following patients will be excluded because of ethical concerns.
•Pregnant or lactating women. The following patients will be excluded to avoid any harm to pregnancy and fetus.
•Patients reporting hypersensitivity to steroids. The following patients will be excluded because intervention includes application of steroids and they can have hypersensitivity or anaphylactic reaction
•Patients taking nonsteroidal anti\-inflammatory drugs in the 3 days before participation in the study. The following patients will be excluded because taking NSAIDS before the treatment will subside the infection and pain and it will act as confounding factor with the study design
•Patients having acute pulpitis, abscesses, or other acute infections. The following patients will be excluded because of ethical concerns.
•Patients with systemic disorders
•Patients on long\-term steroids