Acute Kidney Injury Epidemiology in ICU patients 2
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 10,642
- 试验地点
- 6
- 主要终点
- Occurence rate and maximum severity of AKI within 7 days of ICU admission
研究概览
简要总结
Acute Kidney Injury or AKI is a frequent complication in critically ill patients admitted to the intensive care unit. There are little data on biomarkers, renal replacement therapy and practices are available. The primary objective of this study is to provide a contemporary update on the epidemiology of AKI and associated outcomes in critically ill patients. The secondary object of this study is to assess temporal aspects of AKI, to describe utilization and practice of RRT and to explore differences in rates and outcomes between regions and health care systems according to geographical location and resources. This is an international, multicenter cohort study. Patients who are Age greater than equal to 18 years of age admitted to the participating ICU for more than 24-h, or anticipated length of stay in the ICU for 24 hour or more will be included in the study. The primary outcome of the study is see the occurence rate and maximum severity of AKI within 7 days of ICU admission.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Age more than equal to 18 years 2 Admitted to one of the participating ICUs 3 Admitted to the ICU for more than 24 hours or anticipated length of stay in the ICU for 24 hours or more 4 Informed consent according to local ethical committee.
排除标准
- •1 Readmission to the ICU during the same hospitalization episode 2 End Stage Kidney Disease treated with maintenance RRT 3 Missing AKI defining data no measured serum creatinine and less than 6 hours of documented urinary output.
结局指标
主要结局
Occurence rate and maximum severity of AKI within 7 days of ICU admission
时间窗: Within 7 days of ICU admission
次要结局
- 1 Duration of AKI episodes within first week of ICU admission(2 Proportion of AKI with rapid reversal)
研究者
Dr Deepak Govil
Medanta The Medicity Gurgaon