NL-OMON30486RecruitingNot Applicable
Comparison between beta-adrenergic blockers and angiotensin II receptor antagonists for the treatment of late hypertension in patients with repaired aortic coarctation - Treatment of late hypertension in aortic coarctation
Erasmus MC, Universitair Medisch Centrum Rotterdam0 sites20 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 20
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •- Diagnosis of aortic coarctation (EPCC code 09.29.01)
- •- Previous repair of aortic coarctation
- •- Age 18-80 years
- •- Current use of anti-hypertensive medication (<3 different drugs), or untreated hypertension, defined as systolic >=140 mmHg or diastolic >=90 mmHg
Exclusion Criteria
- •- Known oversensitivity for candesartan or metoprolol
- •- Severe liver insufficiency (ASAT or ALAT >3ULN)
- •- Current use of >=3 anti-hypertensive drugs
- •- Pregnancy or wish to become pregnant
- •- General contraindications for use of candesartan
- •- General contraindications for use of metoprolol (i.e. bradycardia, sick sinus syndrome etc)
Investigators
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