FLUID MANAGEMENT IN DIABETIC KETO- ACIDOSIS: NORMAL SALINE VS SALINE AND LACTATED RINGER

Not Applicable

Recruiting

• Conditions: Nutritional, Metabolic, Endocrine

• Registration Number: PACTR202301531884761
• Lead Sponsor: Souissi Sami

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-05-28
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 230

Inclusion Criteria

Patients of both genders
Aged more than 16 years old
Admitted in the emergency department of moderate to severe ketoacidosis defined by:
hyperglycemia > 2.5 g/L
and Acetonuria > +
and pH< 7.25;
and HCO3- < 15 mmol/l
Anion gap (AG) > 12 mmol/l

Exclusion Criteria

- Patients with chronic renal failure (renal clearance less than 30 ml / minute
- Patients with state of shock defined by: SBP < 90 mmHg with signs of peripheral hypoperfusion.
- The association with severe pathology:
Myocardial ischemia,
Septic shock,
Acute pancreatitis,
Acute surgical pathology.
-Patients transferred before the end of the protocol
- Secondary hemodynamic instability requiring the use of vasoactive drugs
- Withdrawal of consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified