Evaluation of the acceptability, safety and effectiveness of thermal ablation in the prevention of cervical neoplasia in Zimbabwe

International Agency for Research on Cancer0 个研究点目标入组 184 人开始时间: 2021年3月12日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Clinically healthy women aged 25-59 years, not pregnant, with an intact uterus and with no history of debilitating physical and mental illness
•- Screen positive women with colposcopically suspected high-grade lesions (CIN 2/CIN 3) fulfilling the eligibility criteria for ablative treatment. Biopsies will be obtained from the cervical lesion(s) prior to treatment and the results will be reviewed post-treatment.
•- Women with histopathologically confirmed CIN 2/3 fulfilling the eligibility criteria for ablative treatment.
•- Women providing informed consent voluntarily
•The eligibility criteria for ablative treatment are as follows:
•- The entire squamocolumnar junction is visible and the transformation zone is of type 1
•- The lesion does not occupy more than 75% of the cervix and does not extend to the endocervix or vagina
•- There is no evidence of invasive cervical cancer or glandular abnormality

•-Pregnant woman
•-No histological confirmation of CIN2/CIN3
•-Informed consent not provided
•-Suspicion of cervical cancer
•-Lesion not eligible for ablative treatment (large lesion, endocervical lesion, squamocolumnar junction not visible)

发起方

International Agency for Research on Cancer