The Effects of Extremity and "Core" Muscles Strength on Walking and Sit-to-Stand Performance in Patients With Multiple Sclerosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Gazi University
- Enrollment
- 87
- Locations
- 1
- Primary Endpoint
- strength of extremity muscles
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Muscle weakness, which is one of the most common symptoms in patients with MS, limits the activities of daily life activities of patients by causing balance and gait disturbance. Lower extremity muscle strengths of MS patients are reported to be weaker than healthy individuals. Broekmans et al. showed that the weakness of the knee flexor and extensor muscles in patients with MS caused a decrease in walking distance and they are important determinants of walking capacity.
The effects of the endurance and strength of core muscles, as well as the extremity muscles, are important on physical performance. The weakness of the extremities and core muscles in MS patients also affects the sit-to-stand performance negatively as well as a decrease in walking speed and capacity.
In this study, it was aimed to investigate the effects of extremity and core muscle strength on walking and sitting-up performance of MS patients.
Detailed Description
Patients with MS between 0-5,5 score according to the Extended Disability Status Scale (EDSS) and healthy individuals of similar age and sex to patients will be included in the study. The strength of the extremity and core muscles, walking capacity, and sit-to-stand performance will be evaluated once. Investigators will use descriptive statistics and t-tests to compare variables between groups. Investigators will examine the correlations between variables using Pearson bivariate correlations. The significance level is set at p\<0,05
Investigators
Cagla Ozkul
Principal Investigator
Gazi University
Eligibility Criteria
Inclusion Criteria
- •Participants who 18-65 years of age
- •MS patients who are ambulatory (Expanded Disability Status Scale score ≤ 5,5 ) in a stable phase of the disease, without relapses in the last 3 month.
Exclusion Criteria
- •Participants who have orthopedic, vision, hearing, or perception problems
Outcomes
Primary Outcomes
strength of extremity muscles
Time Frame: baseline
The isometric strength of lower extremity muscles will be assessed respectively using a hand-held dynamometer (Baseline®, White Plains, New York, USA).
Secondary Outcomes
- 6 minutes walking test(baseline)
- timed up and go test(baseline)
- sit-to-stand test(baseline)
- Side Bridge Test (core muscles endurance)(baseline)
- Modified Biering-Sorensen test (core muscles endurance)(baseline)
- Trunk Flexion Test (core muscles endurance)(baseline)
- Prone bridge test (core muscles endurance)(baseline)