A Randomized, Controlled, Parallel-Group, Investigator-Initiated Trial toEvaluate the Efficacy, and Safety of the Use of Laryngeal Mask Compared toEndotracheal Intubation During Anesthesia in Pediatric Strabismus Surgery toPrevent Clinically Relevant Postoperative Nausea and Vomiting and Emergence Delirium UsingRisk-Adapted Postoperative Nausea and Vomiting Prophylaxis
Not Applicable
- Conditions
- R11T88.5F05.8Nausea and vomitingOther complications of anaesthesiaOther delirium
- Registration Number
- DRKS00029612
- Lead Sponsor
- niversitätsklinikum des Saarlandes, Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 162
Inclusion Criteria
Subjects undergoing elective strabismus surgery under general anesthesia
Exclusion Criteria
Subjects with American Society of Anesthesiologists Physical Status Classification III or higher,
Subjects participating in another clinical trial
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of nausea and vomiting 6 hours postoperative
- Secondary Outcome Measures
Name Time Method Incidence of nausea and vomiting 2 and 24 hours postoperative,<br>Incidence of emergence delir,<br>other adverse events until discharge
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways are involved in postoperative nausea and vomiting in pediatric strabismus surgery using laryngeal masks versus endotracheal intubation?
How does laryngeal mask airway use compare to endotracheal intubation in reducing PONV and emergence delirium with risk-adapted prophylaxis in pediatric strabismus surgery?
Which biomarkers predict response to laryngeal mask versus endotracheal intubation for PONV and emergence delirium prevention in pediatric patients?
What adverse events are associated with laryngeal masks versus endotracheal intubation in pediatric anesthesia for strabismus surgery, and their management strategies?
What antiemetic drug combinations are used alongside laryngeal masks or endotracheal intubation to prevent PONV in pediatric strabismus surgery?