COMPARATIVE EVALUATION OF ENDOCAN AND TNF-ALPHA LEVELS IN CHRONIC PERIODONTITIS PATIENTS WITH TYPE 2 DIABETES MELLITUS

Gayathri K0 个研究点目标入组 75 人开始时间: 待定最近更新: 2021年11月24日

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•1.Minimum number of 15 teeth should be present.
•2.Patients with Generalised Chronic periodontitis exhibiting Probing Pocket depth of more than or equal to 4mm with Clinical attachment level of more than or equal to 3mm in more than 30percent of diseased sites, According to the AAP 1999 World Workshop (Group I)
•3.If more than five sites satisfy the criteria, sample sites were selected based on greater amount of gingival inflammation, probing pocket depth and clinical attachment level.
•4.Chronic periodontitis patient with Type 2 diabetes mellitus exhibiting good and poor control.
•According to American Diabetic Association(ADA) classification of glycaemic control-
•a) Subjects with HbA1c below 7% , as Type 2 diabetics with good control in one group(group II)
•b) Subjects with HbA1c more than 8% , as Type 2 diabetics with poor control in another group(group III)

•1.Patients with other systemic condition or diseases influencing the course of periodontal disease other than diabetes.
•2.Patients with haemoglobinopathies, bleeding and clotting disorders that will influence HbA1c level.
•3.History of periodontal treatment within the previous six months
•4.Antimicrobial therapy immunosuppressants or lipid lowering drugs within the past 3months
•5.Current Smokers who have smoked more than or equal to 100 cigarettes in their lifetime and currently smoke,Former smokers have smoked more than or equal to 100 cigarettes
•6.Heavy alcoholics
•7.Pregnancy and Lactation

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Gayathri K