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Assessment of Efficacy and Safety of HCQ and Antibiotics Administrated to Patients COVID19(+)

Phase 4
Withdrawn
Conditions
Patients With COVID19
Interventions
Registration Number
NCT04351919
Lead Sponsor
Abderrahmane Mami Hospital
Brief Summary

The study will assess the number of patients who become asymptomatic from clinical signs of COVID19 and will assess the efficacy of Hydroxychloroquine (HCQ) and Azithromycine effects on paucisymptomatic patients with ou without co-morbidities

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • confirmed COVID19 (+)
  • Qt<500ms
  • no severity criteria
  • pauci-symptomatique patients
  • signed consent form
Exclusion Criteria
  • no confirmed patient COVID19
  • severity criteria
  • known allegies to macrolides and HCQ
  • Treated with HCQ within 1 month prior to inclusion
  • hepatitis insufficiency
  • Renal insufficiency
  • treatment no indicated with azithro and HCQ
  • hypovolemia
  • complete brach block
  • retinopathia
  • psoriasis
  • pregnancy or breastfeeding

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
HCQ ArmHydroxychloroquine-
HCQ ArmAzithromycin-
Primary Outcome Measures
NameTimeMethod
Evolution of clinical signsat the end of the study treatment - 1 month after inclusion

Low respiratory signs with severity criteria

improvment or healing of clinical signsat the end of the study treatment - 1 month after inclusion

no respiratory infectious signs

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Eshmoun Clinical Research Centre/ Hôpital Abderrahmen Mami-Ariana

🇹🇳

Tunis, Tunisia

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